Monogenesis
Hi!
I can't make sense of that: why are a lot of disease monogenic, contrary to other traits like skin color or growth that are polygenic?
What's so special with disease?
Good question!
Without being a biologist, I guess that the answer is that when you change a gene at random, the probability that you create malfunction is much greater than the probability that you change a visible trait without creating malfunction (in the same way as there are many more ways for the world to be unordered than being ordered). Thus monogenic diseases are (relatively) common, while other monogenic traits are rare.
Good response!
I thought that if you changed a aminic acid while coding a gene at random, the chance that the whole protein malfunctions and does not influence the rest was greater.
I try your response with the biology teacher :)
